Adapted from William's Gynaecology (Schorge et al., 2008).
Absolute contraindications (Think: Where does estrogen act, how is it broken down)
1. Breast, endometrial, ovarian cancer
2. DVT / PE
4. CVD / Stroke
5. Hypersensitivity to estrogen
6. Liver dysfunction or disease (estrogen metabolised by liver)
7. Undiagnosed abnormal genital bleeding
Relative contraindications (Think: Gallbladder, Liver, Heart, Kidney, Thyroid problems)
1. Prior endometriosis
2. Gallbladder disease
3. Hepatic hemangiomas
4. Prior cholestatic jaundice
5. Hypertriglyceridemia
6. Fluid retention + cardiac or renal dysfunction
7. Hypothyroidism
8. Severe hypocalcemia
9. Dementia
Absolute contraindications (Think: Where does estrogen act, how is it broken down)
1. Breast, endometrial, ovarian cancer
2. DVT / PE
4. CVD / Stroke
5. Hypersensitivity to estrogen
6. Liver dysfunction or disease (estrogen metabolised by liver)
7. Undiagnosed abnormal genital bleeding
Relative contraindications (Think: Gallbladder, Liver, Heart, Kidney, Thyroid problems)
1. Prior endometriosis
2. Gallbladder disease
3. Hepatic hemangiomas
4. Prior cholestatic jaundice
5. Hypertriglyceridemia
6. Fluid retention + cardiac or renal dysfunction
7. Hypothyroidism
8. Severe hypocalcemia
9. Dementia